The Katastrophe brothers are secondary antagonists in the show, and are Spite's lackeys. They are:
- Khaos: A bull/Minotaur type creature.
- Kalamity: A vulture. Seems to trade off the "Smart one" role with Khaos quite frequently.
- Konfusion: A lizard and the dumbest of the three (hence the name).
When the three come in contact with water at the same time, they morph into a large chimera form called the Katastrophe monster. They can only return to normal when the "Plug" (a ponytail type thing on the back of the monster's neck) is pulled out and the water is drained.